|
KMID : 0361619760110010110
|
|
Journal of the Korean Orthopaedic Association
1976 Volume.11 No. 1 p.110 ~ p.115
|
|
|
The Effect of Intra-articular Injection of Steroid on Lysozyme Activity in Patient with Rheumatoid Arthritis
|
|
|
|
|
Abstract
|
|
|
The Lysozyme activities of knee joint fluid in normal Korean people, patient with rheumatoid arthritis, and patients with degenerative arthritis have been reported by Lee6~ in 1974.
This time I have studied the chronologic changes of Lysozyme activity of knee joint fluid in patients with rheumatoid arthritis following intra-articular injection of steroid preparation (6-methylprednisolone~acetate).
The results obtained were as follows.
1. The synovial concentration of Lysozyme in patients with rheumatoid arthritis was found to be 10.88 mcg/ml which is higher than normal value of 8.69 mcg/ml.
2. The Lysozyme activity of joint fluid obtained 5 days after intra-articular injection of steroid prepatation was variable ranging from 7.40 mcg/ml to lO.Omcg/ml with the average of g. 97 mcg/ml, which corresponded to the relief of clinical manifestations.
3. The Lysozyme activity of joint fluid obtained 10 days after intra-articular injection of steroid preparation decreased to 8.3G mcg.´ml on average with the range from 7.60 to 9.30 mcg/ml which was in accordance with much relief of clinical manifestations.
4. The lysozyma activity of joint fluid obtained 20 days after intra-articular steroid injection was 9.55 mcg/ml on averags with the range from 8.25 to 11.25 mcg/ml which was in accordance with the aggravations of clinical manifestations.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|